During skin collagen fiber repair process, hyperplastic fibroblasts and granulation tissue will be f...
During skin collagen fiber repair process, hyperplastic fibroblasts and granulation tissue will be fibrosis, and after deposition, scars are formed.
Firstly, let's comprehend details of skin: The skin is made up of a number of different functional cells, they all live in extracellular matrix(ECM). And in ECM, there are a variety of tissue proteins. Collagen secreted by fibroblasts is one of the tissue proteins, it can support the cells and make the skin smooth and flexible. when the skin is injured, the organizational structure of the collagen fibers was broken, the skin will start repair progress. A scar is formed during the repair progress of collagen fibers. In detail, wound healing is divided into four steps: blood clotting (hemostasis), inflammation, tissue growth (proliferation) and tissue remodeling (maturation).
1.blood clotting (hemostasis): when the occurrence of skin damage, platelets will immediately gather in the damaged parts of the blood vessels, activate collagen to bind platelets and thrombosis, blocking blood vessel rupture in place to help blood clotting. At this time, a layer of collagen matrix is formed around the thrombus, we will find that our wounds are no longer bleeding.
2.Inflammation: Immune cells engulf pathogens such as necrotic cells and bacterial. We will see the wound is red and accompanied by a small amount of scab.
3. Tissue growth (proliferation): Platelets secrete growth factors to promote cell division and proliferation, the secretion of growth factors promotes the granulation tissue and myofibroblasts continue to proliferate, stretch the wound. A scar is formed at this step.
4.Tissue remodeling (maturation): During maturation and remodeling, collagen is realigned along tension lines, and cells that are no longer needed are removed by programmed cell death or apoptosis.
In fact, properly handled wounds will not leave any obvious traces, the wound will slowly be replaced by a new organization.
However, if in inflammation step, wound repeated infection, it will continuously stimulate the secretion of growth factors, fibroblasts and granulation tissue will be hyperplasia, disorderly collagen fibers are rearranged, excessive proliferation of fibroblasts and granulation tissue will be fibrosis, and after deposition, scars are formed.
According to the above scar formation process, We can notice that there are two main points to prevent scar formation: Reduce the incidence of inflammation and shorten the healing time. So that prevent fibroblasts and bean sprouts from hyperplasia.
So, how should the correct handling of a wound, reduce the chance of scar appear?
Quickly clean the wound with the correct method
We need to clean the wound quickly after the injury to avoid infection. Because of infection, it will certainly lengthen the period of inflammation.
Specific methods: We can use the tweezers with alcohol disinfection remove the visible stone or other debris firstly, then wipe the wound with water or saline, then, sterilize with a cotton swab dipped in iodophor. Note! There is no need to use hydrogen peroxide, alcohol or iodine.
If the skin is deeply pierced, cannot stop bleeding or you can see fat, muscle, or internal tendons ligaments or bones or the wound was torn or jagged and so on. Don't hesitate to find a doctor for help!
Keep the wound moist
Use Vaseline or keep the wound moist and can shorten the healing time of the wound and prevent excessive scab.
Properly wrap the wound
Use Dermlin wound dressing can prevent infection and promote wound healing, so that can reduce the formation of scars. The specially designed structure can rapidly absorb the blood and inhibit the growth of bacteria. Active ingredients can promote healing and growth of granulation tissue.
First, do not rub the wound repeatedly, even if it has begun to heal. As the wound heals, you may have an itchy feeling, do not use hand or with a towel and other things rubbing itch this time. New organizations are sensitive and fragile, repeated friction can cause telangiectasia, cell proliferation and increased scar risk.
At the same time, sun exposure should be avoided. UV in the sun will slow down the wound healing process and stimulates cells to produce pigments, leading to pigmentation. Even if the wound has been healed, but also smear sunscreen, protect the fragile new skin.
In the diet, avoid drinking, smoking and spicy food. These will slow the wound healing rate, will also significantly promote fiber proliferation and some inflammatory response, leading to the formation of scars.